Substance Abuse

Kratom Addiction: Signs & What to Expect at a Treatment Facility

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Yes. Kratom acts on the brain’s opioid receptor sites and causes tolerance, physical dependence, and withdrawal symptoms with continued use. Clinical recognition of kratom addiction is increasing, and it is generally treated similarly to other forms of opioid use disorder.

Dependence may develop anywhere from several weeks to months of continuous use, depending upon the person — higher doses and more frequent use increase the likelihood of dependence developing faster. Many people don’t realize they are dependent until they attempt to quit or reduce their use and experience withdrawal symptoms.

Withdrawal from kratom is similar in nature to withdrawal from opioids: muscle pain and weakness, sweats, runny nose, watery eyes, restless legs, anxiety, inability to sleep, stomach cramping, nausea, and intense cravings. Withdrawal symptoms usually begin 12 to 24 hours after last use, reach a peak in the first couple of days, and decrease over one to two weeks. It is common for some symptoms to continue longer without medical support.

While kratom withdrawal is unlikely to be life-threatening, it is uncomfortable enough that many people return to using it simply because they cannot tolerate the symptoms. Having a supportive environment during the initial stages of stopping is extremely helpful.

The combination of placement in a monitored detox setting, entering residential care at an accredited kratom addiction treatment facility, medication-assisted treatment where indicated, evidence-based therapies such as CBT, individual and group therapy, trauma-informed care, and dual diagnosis services for co-occurring mental health issues — all combined together in an evidence-based program.

[1] [3] National Institute on Drug Abuse. (2025). Kratom DrugFacts. https://nida.nih.gov/publications/drugfacts/kratom

[2] Drug Enforcement Administration. (2025, January). Kratom drug fact sheet. U.S. Department of Justice. https://dea.gov/sites/default/files/2025-01/Kratom-Drug-Fact-Sheet.pdf

[4] U.S. Food and Drug Administration. (2025, December 2). FDA and kratom. https://fda.gov/news-events/public-health-focus/fda-and-kratom

[5] Heflin, J. O. (2023). Kratom regulation: Federal status and state approaches. Congressional Research Service. https://d27r7ebsgu0es2.cloudfront.net/reports/LSB11082.html

[6] [8]Singh, D., Müller, C. P., & Vicknasingam, B. K. (2014). Kratom (Mitragyna speciosa) dependence, withdrawal symptoms and craving in regular users. Drug and Alcohol Dependence, 139, 132–137. https://doi.org/10.1016/j.drugalcdep.2014.03.017

[7] Grundmann, O. (2017). Patterns of kratom use and health impact in the US—Results from an online survey. Drug and Alcohol Dependence, 176, 63–70. https://doi.org/10.1016/j.drugalcdep.2017.03.007

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