Substance Abuse

Understanding Meth Addiction and Treatment

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Evidence indicates that effective treatment programs for methamphetamine abuse combine residential clinical services, behavioral interventions such as CBT and contingency management, dual diagnosis treatment for co-occurring psychiatric conditions, medications when appropriate, and post-treatment follow-up. No single component by itself consistently produces successful outcomes — comprehensive, multi-level approaches provide the best results.

Yes. A methamphetamine overdose can cause serious physical harm and potentially death. Common signs of overdose include extremely rapid heart rate, high blood pressure, chest pain, hyperthermia, and seizure activity that can lead to stroke or cardiac arrest. The risk of overdose increases with higher doses and is greatly elevated when meth is used alongside other substances — especially opioids. Call 911 immediately if you believe someone is experiencing a meth overdose.

Typically, acute withdrawal symptoms — physical fatigue, mood disturbances, and intense cravings — peak within one to two weeks. Emotional and motivational disturbance may continue for several weeks or longer until the brain’s dopamine system returns to normal. The quality and duration of withdrawal are greatly improved with comprehensive treatment.

Currently, there is no FDA-approved medication for treating methamphetamine use disorder. Research is ongoing and shows promising findings for certain medication combinations, such as bupropion and naltrexone. 

The most helpful thing you can do is stay connected while avoiding unhealthy behaviors, seek support for yourself to avoid burnout, educate yourself about this disease, and encourage them to seek professional help. We welcome inquiries from family members regarding how they can best communicate with their loved ones to encourage entry into treatment.

[1] [2] National Institute on Drug Abuse. (2024, November 20). Methamphetamine research report: What is methamphetamine? U.S. Department of Health and Human Services. https://nida.nih.gov/publications/research-reports/methamphetamine/what-methamphetamine

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[5] Volkow, N. D., Chang, L., Wang, G. J., Fowler, J. S., Leonido-Yee, M., Franceschi, D., … & Logan, J. (2001). Association of dopamine transporter reduction with psychomotor impairment in methamphetamine abusers. American Journal of Psychiatry, 158(3), 377–382. https://doi.org/10.1176/appi.ajp.158.3.377

[6] National Library of Medicine. (n.d.). Methamphetamine. MedlinePlus.
https:medlineplus.gov/druginfo/meds/a615002.html

[8] Salo, R., Flower, K., Kielstein, A., Leamon, M. H., Nordahl, T. E., & Galloway, G. P. (2011). Psychiatric comorbidity in methamphetamine dependence. Psychiatry Research, 186(2–3), 356–361. https://doi.org/10.1016/j.psychres.2010.09.014

[9] [10] Richards, J. R., & Laurin, E. G. (2023). Methamphetamine toxicity. StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK430895/ 

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